What are Turkey Tail Mushrooms?
Turkey tail mushrooms (Trametes versicolor) are a type of fungi that belong to the Polyporaceae family. They are widely distributed and can be found in forests around the world, growing on decaying logs, tree stumps, and branches. The name "turkey tail" comes from their unique appearance, as the fan-shaped caps of these mushrooms often display concentric rings of various colors that resemble the pattern of a turkey's tail feathers.
Turkey tail mushrooms have been used for centuries in traditional medicine, particularly in Asian cultures such as traditional Chinese medicine and Japanese herbal medicine. They are valued for their potential medicinal properties and have been studied for their immune-boosting and health-promoting effects.
These mushrooms contain various bioactive compounds, including polysaccharides (such as beta-glucans), which are believed to contribute to their potential health benefits. Research suggests that turkey tail mushrooms may have immunomodulatory effects, meaning they can help regulate and enhance the immune system's function. Because of this, they have been investigated for their potential role in supporting immune health and as complementary treatments for conditions like cancer and metabolic illnesses.
What are the Common Medicinal Uses of Turkey Tail?
In traditional Chinese medicine, turkey tail mushrooms have been employed to support overall health and bolster immune function. Their use in this context is deeply rooted in the concept of holistic wellness and balance within the body.
In recent times, modern scientific research has further illuminated the potential of turkey tail mushrooms. Studies have explored their applications as adjunct treatments for conditions like cancer, where they are investigated for their potential to enhance the efficacy of conventional therapies and improve the overall quality of life for patients.
One particularly noteworthy application is their use alongside standard cancer treatments to support immune function and mitigate treatment-related side effects. In regions like Japan, turkey tail mushrooms have been integrated into complementary cancer care protocols, with the aim of extending patient survival rates and enhancing their well-being during treatment.
Turkey Tail Mushrooms May Boost Immune System Health
Turkey tail mushrooms contain polysaccharides that have been extensively investigated for their potential to boost the health of the immune system. Among these compounds, Polysaccharide Krestin (PSK) from turkey tail has garnered particular attention due to its high biological activity . PSK's effectiveness is so notable that Japan has classified it as an approved adjunct to cancer care as its ability to fortify the immune system has contributed to the extended well-being of individuals fighting cancer . Moreover, the holistic impact of turkey tail extends beyond PSK alone, as use of the entire mushroom has been demonstrated to enhance both innate and adaptive immune responses . This dual action enhances our body's primary and secondary lines of defense, enhancing our resilience against harmful pathogens overall.
Turkey tail mushrooms also contain another significant polysaccharide protein complex known as PSP, enriched with substantial amounts of beta-glucans. Research indicates that these immune-activating agents have the remarkable ability to stimulate the production of nitric oxide (NO) and inducible nitric oxide synthase (iNOS) in macrophages treated with turkey tail. This activation allows the macrophages to efficiently phagocytize and kill bacteria . In fact, this research study predicts that turkey tail’s antibacterial activities open the door to using it as an alternative to antibiotics in certain drug-resistant bacteria. Macrophages, specialized cells responsible for identifying and eliminating pathogenic organisms, possess specific receptors such as dectin-1 and TLR-2, designed to interact with beta-glucans . The engagement of these receptors by beta-glucans sets in motion processes that culminate in the elimination of pathogenic microorganisms .
Antibodies are specialized proteins within our bloodstream that our bodies generate upon encountering foreign pathogens. Their primary mission is to combat and eradicate these microorganisms from our system if we come into contact with them. Notably, turkey tail has been identified as a substance that can augment the production of antibodies, particularly IgM and IgG . The latter antibody type, IgG, constitutes a significant portion, approximately 75%, of the serum antibodies present in humans . These antibodies are the immune system's molecular warriors, mobilized in response to the presence of foreign pathogens, and they function to neutralize and remove these intruders from our body.
The significance of turkey tail's ability to enhance antibody production becomes particularly apparent in scenarios where our body encounters novel pathogens or viruses. If turkey tail indeed boosts antibody production in response to these encounters, it implies that our immunity could be prolonged, safeguarding us against the risk of reinfection over extended periods.
Turkey Tail May Provide Powerful Antioxidant and Anti-inflammatory Support
Turkey tail boasts an impressive array of antioxidants, which are compounds that shield our cells from harm and inflammation. The balance between antioxidants and unstable molecules is crucial for our immune system's well-being...
Turkey Tail May Enhance Cardiovascular Health
Due to its capacity to counter oxidative stress and its anti-inflammatory properties, turkey tail mushrooms could potentially contribute to the promotion of cardiovascular well-being. Oxidative stress is widely recognized as a factor that contributes to conditions such as myocardial infarctions, atherosclerosis, myocardial ischemia, and even heart failure...
Turkey Tail Mushroom Effects on Cancer
The use of turkey tail mushrooms in cancer treatment has gained significant attention and research interest. Numerous studies have been conducted, including in vitro investigations, animal experiments, and human clinical trials, contributing to a substantial body of knowledge regarding their potential benefits in various forms of cancer, such as gastrointestinal, breast, and lung cancers...
Turkey Tail May Improve Health of the Gut Microbiome
Turkey tail mushrooms have been investigated for their potential to function similarly to prebiotics. Unlike probiotics, which contain live bacteria, prebiotics aid in promoting the growth of beneficial bacteria within the gastrointestinal tract...
Turkey Tail as an Adaptogen May Protect the Body from Prolonged Stress
Adaptogens, compounds recognized for their ability to protect the human body against a broad spectrum of external stressors, achieve this by influencing both the immune-neuro-endocrine system and the hypothalamic-pituitary-adrenal axis ...
Turkey Tail May Prevent Complications of Type 2 Diabetes Mellitus (T2DM)
There is existing research on PSP derived from turkey tail mushroom focusing on the effects of this compound on oxidative stress and glucose regulation in type 2 diabetes mellitus (T2DM)...
Turkey Tail Capsules
Eversio Wellness’ product DEFEND NOW is a 12:1 extract of turkey tail containing high percentages of beta-D-glucans and polysaccharide peptide (PSP). The mushroom extract is made from 100% fruiting body only, ensuring there are no fillers or additives that may lessen the potency and therapeutic effect of the product. By taking 2 capsules per day, it is an easy addition for anyone looking to improve immune health, health of the gut microbiome, and protect against the complications of oxidative stress.
Turkey Tail Powder
Eversio Wellness offers one mushroom extract blend containing turkey tail:
Oyster Mushrooms Extract Powder
1) AWAKEN Blend
The AWAKEN blend was thoughtfully crafted to elevate your morning rituals and enhance overall well-being. Containing the combination of Lion’s Mane, Turkey Tail, and Cordyceps mushrooms, this blend is designed to support mental agility, boost energy levels, and fortify your immune system.
Turkey Tail Health Benefits Summary
Turkey tail mushroom supplements offer a range of potential health benefits that stem from their bioactive compounds and interactions with the body's systems. These benefits include:
1) Immune System Support: Turkey tail mushrooms are rich in polysaccharides, including Polysaccharide Krestin (PSK) and Polysaccharide Peptide (PSP), which have been shown to stimulate and modulate the immune system. They can enhance the production of immune cells, improve immune response, and promote overall immune system health.
2) Antioxidant Properties: The antioxidants present in turkey tail mushrooms help combat oxidative stress and reduce damage caused by free radicals. This can contribute to healthier cells and tissues and may play a role in preventing chronic diseases.
3) Cancer Support: Some studies suggest that turkey tail mushrooms may have anti-cancer properties. The compounds in these mushrooms can help inhibit the growth of cancer cells and support conventional cancer treatments. They are particularly known for their potential to enhance the immune response against cancer cells.
4) Digestive Health: Turkey tail mushrooms contain prebiotics, which promote the growth of beneficial gut bacteria. A healthy gut microbiome is associated with improved digestion, nutrient absorption, and overall digestive well-being.
5) Antimicrobial Activity: Turkey tail mushrooms possess natural antimicrobial properties that can help the body fight off infections and harmful microorganisms. They may contribute to a stronger defense against various pathogens.
6) Anti-Inflammatory Effects: Compounds in turkey tail mushrooms have demonstrated anti-inflammatory properties, which can help reduce chronic inflammation and its associated health risks.
7) Liver Health: Some studies indicate that turkey tail mushrooms may support liver health by promoting detoxification and reducing oxidative stress in the liver.
8) Stress Adaptation: Turkey tail mushrooms are considered adaptogens, which means they may help the body better adapt to stress and maintain balance. This can contribute to improved mental and physical resilience.
9) Overall Well-Being: The combined effects of immune support, antioxidant activity, and various other potential benefits contribute to an overall sense of well-being and vitality.
Recommended Dosages of Turkey Tail Mushrooms
For optimal consumption, Eversio Wellness advises individuals to limit their intake of dried turkey tail fruiting body to a maximum of 27,000 mg per day. Their turkey tail product, DEFEND NOW, boasts an impressive composition of 53% beta-glucans and 11% PSP. Eversio Wellness recommends a daily consumption of 1000 mg of their turkey tail mushroom extract, which is equivalent to a crude quantity of 12,000 mg.
Where to Buy Quality Turkey Tail Mushroom Supplements
In the vast market of medicinal mushrooms, it is important to prioritize awareness of the product's composition to ensure the highest potency. At Eversio Wellness, their commitment lies in offering exclusively 100% fruiting body mushroom extracts, maintaining a transparent approach towards consumers by providing Certificates of Analysis (COAs) for each product. These COAs serve as a reassurance, scientifically confirming the claimed percentages of beneficial constituents through laboratory testing. Furthermore, the COAs also verify the absence of heavy metals and microbial contaminants, assuring customers of receiving the finest mushroom supplements available.
Turkey Tail Extract in Powder or Capsules
Eversio Wellness offers Turkey Tail as one of 3 mushrooms in our Awaken Blend or in a therapeutic dose capsule in Defend Now.
Health and Safety of Turkey Tail Mushrooms
Turkey tail mushroom supplements have garnered attention for their potential health benefits, particularly in supporting immune function, antioxidant activity, and overall well-being. While turkey tail supplements offer exciting possibilities, it's important to prioritize health and safety. As with any dietary supplement, it's recommended to consult a healthcare professional before incorporating turkey tail supplements into your routine, especially if you have underlying health conditions or are taking medications. While generally considered safe, potential side effects and interactions should be carefully considered. Additionally, sourcing reputable and high-quality supplements is crucial to ensure efficacy and minimize risks. Maintaining moderation and adhering to recommended dosages is advised, as excessive consumption could potentially lead to adverse effects. By approaching turkey tail mushroom supplements with informed caution, individuals can explore their potential benefits while prioritizing their overall health and well-being.
-  PDQ Integrative, Alternative, and Complementary Therapies Editorial Board. Medicinal Mushrooms (PDQ®): Patient Version. 2022 Jul 29. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK424937/
-  Benson KF, Stamets P, Davis R, Nally R, Taylor A, Slater S, Jensen GS. The mycelium of the Trametes versicolor (Turkey tail) mushroom and its fermented substrate each show potent and complementary immune activating properties in vitro. BMC Complement Altern Med. 2019 Dec 2;19(1):342. doi: 10.1186/s12906-019-2681-7. PMID: 31791317; PMCID: PMC6889544.
-  Shao-Hua Shi, Wen-Tao Yang, Ke-Yan Huang, Yan-Long Jiang, Gui-Lian Yang, Chun-Feng Wang, Yu Li. Beta-Glucans from Coriolus versicolor protect mice against S. typhimurium challenge by activation of macrophages. International Journal of Biological Macromolecules, Volume 86, 2016, Pages 352-361. ISSN 0141-8130. https://doi.org/10.1016/j.ijbiomac.2016.01.058.
-  Mirończuk-Chodakowska I, Kujawowicz K, Witkowska AM. Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era. Nutrients. 2021 Nov 6;13(11):3960. doi: 10.3390/nu13113960. PMID: 34836215; PMCID: PMC8623785.
-  Habtemariam S. Trametes versicolor (Synn. Coriolus versicolor) Polysaccharides in Cancer Therapy: Targets and Efficacy. Biomedicines. 2020 May 25;8(5):135. doi: 10.3390/biomedicines8050135. PMID: 32466253; PMCID: PMC7277906.
-  Bendich A. Physiological role of antioxidants in the immune system. J Dairy Sci. 1993 Sep;76(9):2789-94. doi: 10.3168/jds.S0022-0302(93)77617-1. PMID: 8227682.
-  Rašeta M, Popović M, Knežević P, Šibul F, Kaišarević S, Karaman M. Bioactive Phenolic Compounds of Two Medicinal Mushroom Species Trametes versicolor and Stereum subtomentosum as Antioxidant and Antiproliferative Agents. Chem Biodivers. 2020 Dec;17(12):e2000683. doi: 10.1002/cbdv.202000683. Epub 2020 Nov 17. PMID: 33058392.
-  Pérez-Cano FJ, Castell M. Flavonoids, Inflammation, and Immune System. Nutrients. 2016 Oct 21;8(10):659. doi: 10.3390/nu8100659. PMID: 27775647; PMCID: PMC5084045.
-  Li Y, Yao J, Han C, Yang J, Chaudhry MT, Wang S, Liu H, Yin Y. Quercetin, Inflammation, and Immunity. Nutrients. 2016 Mar 15;8(3):167. doi: 10.3390/nu8030167. PMID: 26999194; PMCID: PMC4808895.
-  Dubois-Deruy E, Peugnet V, Turkieh A, Pinet F. Oxidative Stress in Cardiovascular Diseases. Antioxidants (Basel). 2020 Sep 14;9(9):864. doi: 10.3390/antiox9090864. PMID: 32937950; PMCID: PMC7554855.
-  Senoner T, Dichtl W. Oxidative Stress in Cardiovascular Diseases: Still a Therapeutic Target? Nutrients. 2019 Sep 4;11(9):2090. doi: 10.3390/nu11092090. PMID: 31487802; PMCID: PMC6769522.
-  Standish LJ, Wenner CA, Sweet ES, Bridge C, Nelson A, Martzen M, Novack J, Torkelson C. Trametes versicolor mushroom immune therapy in breast cancer. J Soc Integr Oncol. 2008 Summer;6(3):122-8. PMID: 19087769; PMCID: PMC2845472.
-  Guggenheim AG, Wright KM, Zwickey HL. Immune Modulation From Five Major Mushrooms: Application to Integrative Oncology. Integr Med (Encinitas). 2014 Feb;13(1):32-44. PMID: 26770080; PMCID: PMC4684115.
-  Pallav K, Dowd SE, Villafuerte J, Yang X, Kabbani T, Hansen J, Dennis M, Leffler DA, Newburg DS, Kelly CP. Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers: a randomized clinical trial. Gut Microbes. 2014 Jul 1;5(4):458-67. doi: 10.4161/gmic.29558. Epub 2014 Jul 9. PMID: 25006989.
-  Liao LY, He YF, Li L, Meng H, Dong YM, Yi F, Xiao PG. A preliminary review of studies on adaptogens: comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide. Chin Med. 2018 Nov 16;13:57. doi: 10.1186/s13020-018-0214-9. PMID: 30479654; PMCID: PMC6240259.
-  Chu B, Marwaha K, Sanvictores T, et al. Physiology, Stress Reaction. [Updated 2022 Sep 12]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK541120/
-  Lo HC, Hsu TH, Lee CH. Extracellular Polysaccharopeptides from Fermented Turkey Tail Medicinal Mushroom, Trametes versicolor (Agaricomycetes), Mitigate Oxidative Stress, Hyperglycemia, and Hyperlipidemia in Rats with Type 2 Diabetes Mellitus. Int J Med Mushrooms. 2020;22(5):417-429. doi: 10.1615/IntJMedMushrooms.2020034560. PMID: 32749097.