What are Tremella Mushrooms?
The Tremella mushroom, also referred to as Silver Ear or Snow Fungus, is a distinctive type of functional mushroom originating from Asia, specifically China. These unique mushrooms grow naturally on trees and possess a translucent, gelatinous appearance resembling jelly. They have garnered significant attention in the Western world in recent times, as individuals actively seek out natural approaches to enhance their overall health and well-being. From fortifying the immune system and nurturing skin health to facilitating chronic disease, the benefits attributed to Tremella mushrooms make them a compelling addition to any wellness regimen.
What Are the Tremella Mushroom Benefits?
Tremella mushrooms boast a long-standing history in Traditional Chinese Medicine (TCM), spanning countless centuries, primarily due to their diverse health advantages. Within the realm of TCM, Tremella mushrooms are revered for their ability to nourish the body's yin energy, which encompasses attributes like coolness, moisture, and rejuvenation. Consequently, these mushrooms are frequently used to promote vibrant skin and anti-aging from the inside out. Moreover, Tremella mushrooms are believed to play a vital role in supporting digestive health and facilitating efficient digestion.

Tremella May Promote Overall Skin Health
I'm sure most of you are familiar with the significance of antioxidants and their crucial role in maintaining our well-being. These remarkable compounds assist our bodies in balancing out unstable molecules, thus reducing the potential harm they can inflict on our health. When free radicals overpower our systems, it can lead to oxidative stress, which, if left unchecked, may result in cellular damage. These unstable molecules, known as free radicals, possess the ability to disrupt our cells and DNA, contributing to premature aging and the onset of diseases [1].
Tremella mushrooms have long been associated with enhancing skin health, thanks to their exceptional hydrating and antioxidant properties. In China, this functional mushroom has been valued for thousands of years for its beneficial effects on the skin, immune system, and disease prevention [2]. Recent studies have shed light on Tremella's remarkable capabilities, including its ability to modulate inflammation, promote wound healing, combat oxidation, slow down the aging process, and even provide protection against radiation [2]. Remarkably, Tremella polysaccharides are also commonly utilized in the realm of topical skincare and cosmetics, serving as valuable moisturizing additives [2].
One of the fundamental pillars of effective skincare revolves around the diligent use of sunscreen. Shielding our skin from sunspots and various forms of sun damage is paramount to maintaining its health, as any compromise to our skin's protective barrier can potentially lead to skin cancer and premature aging. UVA radiation, a prominent environmental factor, has the potential to induce oxidative stress on our skin [3]. Oxidative stress plays a significant role in the aging process, manifesting as both internal and external signs of aging [3]. This stress occurs when the body's antioxidant system is overwhelmed by an excess of oxidants, including free radicals, resulting in cellular damage [3]. Aging actually renders us more susceptible to oxidative stress, as biochemical and physiological processes gradually decline, creating an imbalance between free radicals and antioxidants within the body [4].

I'm sure most of you are familiar with the significance of antioxidants and their crucial role in maintaining our well-being. These remarkable compounds assist our bodies in balancing out unstable molecules, thus reducing the potential harm they can inflict on our health. When free radicals overpower our systems, it can lead to oxidative stress, which, if left unchecked, may result in cellular damage. These unstable molecules, known as free radicals, possess the ability to disrupt our cells and DNA, contributing to premature aging and the onset of diseases [1].
Tremella mushrooms have long been associated with enhancing skin health, thanks to their exceptional hydrating and antioxidant properties. In China, this functional mushroom has been valued for thousands of years for its beneficial effects on the skin, immune system, and disease prevention [2]. Recent studies have shed light on Tremella's remarkable capabilities, including its ability to modulate inflammation, promote wound healing, combat oxidation, slow down the aging process, and even provide protection against radiation [2]. Remarkably, Tremella polysaccharides are also commonly utilized in the realm of topical skincare and cosmetics, serving as valuable moisturizing additives [2].
One of the fundamental pillars of effective skincare revolves around the diligent use of sunscreen. Shielding our skin from sunspots and various forms of sun damage is paramount to maintaining its health, as any compromise to our skin's protective barrier can potentially lead to skin cancer and premature aging. UVA radiation, a prominent environmental factor, has the potential to induce oxidative stress on our skin [3]. Oxidative stress plays a significant role in the aging process, manifesting as both internal and external signs of aging [3]. This stress occurs when the body's antioxidant system is overwhelmed by an excess of oxidants, including free radicals, resulting in cellular damage [3]. Aging actually renders us more susceptible to oxidative stress, as biochemical and physiological processes gradually decline, creating an imbalance between free radicals and antioxidants within the body [4].

Tremella May Boost Immune System Function
Tremella mushroom serves as a remarkable natural reservoir of beta-glucans, complex polysaccharides renowned for their immune-boosting properties. These beta-glucans stimulate key immune cells like macrophages and natural killer cells, bolstering the immune response. Moreover, they have been shown to elevate the production of cytokines, crucial signaling molecules that coordinate and fine-tune immune reactions [7]...
Tremella Possesses Anti-Inflammatory Effects
Tremella mushroom offers significant anti-inflammatory benefits. The presence of Tremella polysaccharides has been shown to exhibit antioxidative stress and anti-inflammatory effects in macrophages treated with LPS, functioning by inhibiting the miR-155 and NFκB pathways [9]. These findings suggest that Tremella polysaccharides hold potential as a therapeutic agent for the treatment of inflammation-related diseases...
Tremella’s Current Role in Medical Treatment and Health Care
Tremella mushroom is highly valued in the medical field due to its polysaccharide content. Some Tremella polysaccharide-based medicines have been approved for clinical treatment. For instance, in China, Tremella Polysaccharide Enteric Capsule has been approved for treating leukopenia in cancer patients undergoing chemotherapy and radiation therapy, as well as chronic persistent and active hepatitis [9]...
Tremella May Promote the Growth of Healthy Gut Bacteria
Tremella may hold a role in regulating intestinal flora. One study found that Tremella may significantly increase the diversity of gut bacteria and restore levels of Lactobacillus, Odoribacter, Helicobacter, Ruminococcaceae, and Marinifilaceae [10]...
Tremella May Help Treat Chronic Diseases
Tremella mushroom shows promising potential in the treatment of chronic diseases, particularly hyperglycemia, hyperlipidemia, and obesity. Research studies have demonstrated significant benefits of Tremella polysaccharides in addressing these health concerns.
Tremella May Provide Neurotrophic Effects
Tremella mushroom has garnered attention for its notable neurotrophic and neuroprotective effects, as supported by compelling research findings. In one study, extracts derived from Tremella's fruiting bodies showcased remarkable behavioral and structural changes compared to a placebo group [13]...
Tremella Extract Mushroom Capsules
Eversio Wellness’ product EVERGLOW NOW is an 8:1 extract of Tremella mushroom containing high percentages of beta-glucans and other bioactive constituents. The mushroom extract is made from 100% fruiting body only, ensuring there are no fillers or additives that may lessen the potency and therapeutic effect of the product. By taking 2 capsules per day, it is an easy addition for anyone looking to enhance overall skin health, fight the signs of aging, strengthen the immune system, and prevent against development of chronic disease.

Tremella Mushroom Extract Powder
Eversio Wellness offers one mushroom extract blend containing Tremella:
Oyster Mushrooms Extract Powder
1) REJUVENATE Blend
The REJUVENATE blend is an antioxidant powerhouse that will help individuals rejuvenate from the inside. It contains mushrooms known to have the highest percentages of ergothioneine, terpenes, and triterpenes – anti-aging superstars! This blend contains Tremella alongside Oyster, Chaga, Lion’s Mane, Shiitake, and Maitake mushrooms.

Recommended Dosages of Tremella Mushrooms
For optimal consumption, Eversio Wellness advises individuals to limit their intake of dried Lion's Mane fruiting body to a maximum of 9,000 mg per day. Their Tremella mushroom product, EVERGLOW NOW, boasts an impressive composition of 18% beta-glucans. Eversio Wellness recommends a daily consumption of 1000 mg of their Tremella mushroom extract, which is equivalent to a crude quantity of 8000 mg.

Where to Buy Quality Tremella Mushroom Supplement
In the vast market of medicinal mushrooms, it becomes imperative to prioritize awareness of the product's composition to ensure the utmost potency. At Eversio Wellness, their commitment lies in offering exclusively 100% fruiting body mushroom extracts, maintaining a transparent approach towards consumers by providing Certificates of Analysis (COAs) for each product. These COAs serve as a reassurance, scientifically confirming the claimed percentages of beneficial constituents through meticulous lab testing. Furthermore, the COAs also verify the absence of heavy metals and microbial contaminants, assuring customers of receiving the finest mushroom supplements available. There has never been a more opportune moment to explore the world of online mushroom purchases.

Ways to Consume Tremella Mushrooms
Eversio Wellness offers 2 different Tremella mushroom products, one in capsule form and the other in powder form.
from $59.99 to $64.99
from $59.99 to $64.99
Tremella Mushroom Health and Safety
Tremella mushroom supplements have gained popularity in recent years as individuals seek natural ways to support their health and well-being. When it comes to their health benefits, Tremella mushroom supplements are often associated with immune system support, skin health promotion, and even potential benefits for lung health and digestion. However, it's important to consider the safety aspects as well. Tremella mushroom is generally considered safe for consumption, especially in its natural form as a food ingredient. However, as with any supplement or dietary addition, it is recommended to consult with a healthcare professional before starting any new regimen, especially for individuals with specific medical conditions or those who are pregnant or breastfeeding. Additionally, it is crucial to purchase Tremella mushroom supplements from reputable sources to ensure quality and purity. As with any dietary supplement, it is best to follow the recommended dosage guidelines and discontinue use if any adverse reactions occur. Prioritizing a balanced and varied diet alongside a healthy lifestyle remains essential for overall health and well-being.

Tremella Mushroom: Summary
Tremella mushroom is a remarkable natural resource that offers a multitude of health benefits. Its high content of polysaccharides has drawn significant attention in medical and therapeutic applications. Tremella polysaccharides have been studied extensively and have shown promising effects in various areas. They exhibit immune-boosting properties, regulate blood glucose and lipid levels, and have potential in treating obesity and diabetes. Moreover, Tremella has demonstrated neuroprotective effects, improved learning, memory, and cognitive function while protecting brain neurons. Tremella polysaccharides also have antioxidant and anti-inflammatory properties, which make them valuable for wound healing and treating chronic diseases. Tremella-based medicines have been approved for clinical use, and the mushroom's diverse distribution and absorption in the body make it a versatile ingredient for drug delivery systems. Additionally, Tremella polysaccharides have found application in the development of health products, offering benefits such as immune enhancement and regulation of intestinal flora. Overall, Tremella mushroom stands out as a natural and versatile resource with the potential to support overall well-being and contribute to various therapeutic approaches.
References:
- [1] Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, Squadrito F, Altavilla D, Bitto A. Oxidative Stress: Harms and Benefits for Human Health. Oxid Med Cell Longev. 2017;2017:8416763. doi: 10.1155/2017/8416763. Epub 2017 Jul 27. PMID: 28819546; PMCID: PMC5551541.
- [2] Ma X, Yang M, He Y, Zhai C, Li C. A review on the production, structure, bioactivities and applications of Tremella polysaccharides. Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211000541. doi: 10.1177/20587384211000541. PMID: 33858263; PMCID: PMC8172338.
- [3] Fu H, You S, Zhao D, An Q, Zhang J, Wang C, Wang D, Li M. Tremella fuciformis polysaccharides inhibit UVA-induced photodamage of human dermal fibroblast cells by activating up-regulating Nrf2/Keap1 pathways. J Cosmet Dermatol. 2021 Dec;20(12):4052-4059. doi: 10.1111/jocd.14051. Epub 2021 Mar 25. PMID: 33686752.
- [4] Shen T, Duan C, Chen B, Li M, Ruan Y, Xu D, Shi D, Yu D, Li J, Wang C. Tremella fuciformis polysaccharide suppresses hydrogen peroxide-triggered injury of human skin fibroblasts via upregulation of SIRT1. Mol Med Rep. 2017 Aug;16(2):1340-1346. doi: 10.3892/mmr.2017.6754. Epub 2017 Jun 12. PMID: 28627707; PMCID: PMC5561887.
- [5] Chiang JH, Tsai FJ, Lin TH, Yang JS, Chiu YJ. Tremella fuciformis Inhibits Melanogenesis in B16F10 Cells and Promotes Migration of Human Fibroblasts and Keratinocytes. In Vivo. 2022 Mar-Apr;36(2):713-722. doi: 10.21873/invivo.12757. PMID: 35241526; PMCID: PMC8931924.
- [6] Xie L, Yang K, Liang Y, Zhu Z, Yuan Z, Du Z. Tremella fuciformis polysaccharides alleviate induced atopic dermatitis in mice by regulating immune response and gut microbiota. Front Pharmacol. 2022 Aug 25;13:944801. doi: 10.3389/fphar.2022.944801. PMID: 36091780; PMCID: PMC9452665.
- [7] Akramiene, D., Kondrotas, A., Didziapetriene, J., & Kevelaitis, E. (2007). Effects of beta-glucans on the immune system. Medicina, 43(8), 597.
- [8] Mirończuk-Chodakowska I, Kujawowicz K, Witkowska AM. Beta-Glucans from Fungi: Biological and Health-Promoting Potential in the COVID-19 Pandemic Era. Nutrients. 2021 Nov 6;13(11):3960. doi: 10.3390/nu13113960. PMID: 34836215; PMCID: PMC8623785.
- [9] Ma X, Yang M, He Y, Zhai C, Li C. A review on the production, structure, bioactivities and applications of Tremella polysaccharides. Int J Immunopathol Pharmacol. 2021 Jan-Dec;35:20587384211000541. doi: 10.1177/20587384211000541. PMID: 33858263; PMCID: PMC8172338.
- [10] Xu Y, Xie L, Zhang Z, Zhang W, Tang J, He X, Zhou J, Peng W. Tremella fuciformis Polysaccharides Inhibited Colonic Inflammation in Dextran Sulfate Sodium-Treated Mice via Foxp3+ T Cells, Gut Microbiota, and Bacterial Metabolites. Front Immunol. 2021 Apr 1;12:648162. doi: 10.3389/fimmu.2021.648162. PMID: 33868283; PMCID: PMC8049506.
- [11] Kiho T, Tsujimura Y, Sakushima M, Usui S, Ukai S. [Polysaccharides in fungi. XXXIII. Hypoglycemic activity of an acidic polysaccharide (AC) from Tremella fuciformis]. Yakugaku Zasshi. 1994 May;114(5):308-15. Japanese. doi: 10.1248/yakushi1947.114.5_308. PMID: 8014840.
- [12] Hsu TH, Lee CH, Lin FY, Wasser SP, Lo HC. The Fruiting Bodies, Submerged Culture Biomass, and Acidic Polysaccharide Glucuronoxylomannan of Yellow Brain Mushroom Tremella mesenterica Modulate the Immunity of Peripheral Blood Leukocytes and Splenocytes in Rats with Impaired Glucose Tolerance. J Tradit Complement Med. 2014 Jan;4(1):56-63. doi: 10.4103/2225-4110.124347. PMID: 24872934; PMCID: PMC4032843.
- [13] Hyun-Jung Park, Hyun Soo Shim, Yong Ho Ahn, Kyung Soo Kim, Kum Ju Park, Woong Ki Choi, Hyo-Cheol Ha, Jung Il Kang, Tae Seok Kim, Ik Hyun Yeo, Jin Su Kim, Insop Shim, Tremella fuciformis enhances the neurite outgrowth of PC12 cells and restores trimethyltin-induced impairment of memory in rats via activation of CREB transcription and cholinergic systems, Behavioural Brain Research, Volume 229, Issue 1, 2012, Pages 82-90, ISSN 0166-4328, https://doi.org/10.1016/j.bbr.2011.11.017.
- [14] Oda Y. Choline acetyltransferase: the structure, distribution and pathologic changes in the central nervous system. Pathol Int. 1999 Nov;49(11):921-37. doi: 10.1046/j.1440-1827.1999.00977.x. PMID: 10594838.
- [15] Hawley WR, Witty CF, Daniel JM, Dohanich GP. Choline acetyltransferase in the hippocampus is associated with learning strategy preference in adult male rats. Behav Brain Res. 2015 Aug 1;289:118-24. doi: 10.1016/j.bbr.2015.04.034. Epub 2015 Apr 27. PMID: 25930215.
- [16] Park KJ, Lee SY, Kim HS, Yamazaki M, Chiba K, Ha HC. The Neuroprotective and Neurotrophic Effects of Tremella fuciformis in PC12h Cells. Mycobiology. 2007 Mar;35(1):11-5. doi: 10.4489/MYCO.2007.35.1.011. Epub 2007 Mar 31. PMID: 24015061; PMCID: PMC3763079.